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Thread: New UCSD flu discovery could block illness entirely

  1. #1
    Above the FRAY Friday13's Avatar
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    New UCSD flu discovery could block illness entirely

    New UCSD flu discovery could block illness entirely
    Scientists led by a UC San Diego chemist reported progress recently in researching a universal flu drug, effective regardless of the strain.

    Seth Cohen, a UCSD professor and co-founder of San Diego's Forge Therapeutics, said the drug inhibits a critical viral enzyme by jamming molecular machinery common to all strains. It could reduce the flu's severity or perhaps block it completely.

    The drug blocks an enzyme containing the metal manganese. Such metalloenzymes form the basis of Forge's technology, which is currently directed toward developing antibiotics, not antivirals.

    "This enzyme is a component that allows the virus to steal the cellular machinery, so that the virus can reproduce using the human cells," Cohen said. The drug interrupts this process by binding to the manganese ions.

    ...MORE...

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    Veteran Member TNVolunteer73's Avatar
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    Big Phrama to the rescue again.

  3. #3
    Above the FRAY Friday13's Avatar
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    Quote Originally Posted by TNVolunteer73 View Post
    Big Phrama to the rescue again.
    University of California San Diego is "Big Pharma"?
    Thanks from Panzareta, Madeline and BigLeRoy

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    Spock of Vulcan Ian Jeffrey's Avatar
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    Quote Originally Posted by Friday13 View Post
    University of California San Diego is "Big Pharma"?
    Obviously not, but Forge Therapeutics is a biotech company. Maybe that's what he's talking about.
    Thanks from Puzzling Evidence and Madeline

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    Bad Policy Good Politics DebateDrone's Avatar
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    I heard about the process awhile back. Very promising and interesting.


    UC San Diego Chemist Stirs Hope for a New Flu Treatment
    “One of the major targets has been a particular RNA polymerase subunit that the virus uses,” Cohen said. “It is a nucleic-acid processing protein that is required for the life cycle of the virus, for it to replicate and to propagate, and it is dependent on manganese metal ions.” The subunit relies on two manganese ions to initiate the replication of the genetic information. Scientists have reasoned that a drug that could bind to the manganese ions would shut down the protein’s ability to work, leaving the virus unable to reproduce and spread through the body. This could weaken or perhaps completely stop the virus, thereby treating the flu.
    UC San Diego Chemist Stirs Hope for a New Flu Treatment
    Thanks from Madeline and Friday13

  6. #6
    Bad Policy Good Politics DebateDrone's Avatar
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    Quote Originally Posted by TNVolunteer73 View Post
    Big Phrama to the rescue again.

    Science is out friend.

    The researchers acknowledge funding from the U.S. National Institutes of Health.

    The American Chemical Society is a not-for-profit organization chartered by the U.S. Congress. ACS is a global leader in providing access to chemistry-related information and research through its multiple databases, peer-reviewed journals and scientific conferences. ACS does not conduct research, but publishes and publicizes peer-reviewed scientific studies
    UC San Diego Chemist Stirs Hope for a New Flu Treatment
    Thanks from Madeline, Friday13 and Ian Jeffrey

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    Veteran Member Madeline's Avatar
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    O! This sounds exciting!
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    Veteran Member Madeline's Avatar
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    Quote Originally Posted by TNVolunteer73 View Post
    Big Phrama to the rescue again.
    "Big Pharma" has nothing to do with this discovery. Scientists made it, conducting research paid for by taxpayers.

    Big Pharma will likely find a way to profit off this discovery, though. It's one way the wealth of all of us is stolen by the 0.01%.
    Thanks from BigLeRoy, Friday13 and Frecks1710

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    Veteran Member Puzzling Evidence's Avatar
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    Nice! Rich people will be able to avoid getting the flu! Too bad not everyone will be able to afford this. Sigh....there's always "Theraflu."
    Last edited by Puzzling Evidence; 24th March 2018 at 03:24 PM.

  10. #10
    Bad Policy Good Politics DebateDrone's Avatar
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    Quote Originally Posted by Puzzling Evidence View Post
    Nice! Rich people will be able to avoid getting the flue! Too bad not everyone will be able to afford this. Sigh....there's always "Theraflu."
    One day "Theraflu" could contain the active ingredient[s] needed to slow to stop, the reproduction of the virus.

    Then, Theraflu would actually work.

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